Three sisters in San Francisco discover that they are the foretold "Charmed Ones," the most powerful good witches the world has ever known. Prue, the beautiful and driven oldest sister, Piper, the earthy and creative middle sister, and Phoebe, the free-spirited youngest, could not be further apart in how they view the world and each other but they must band together to battle the dark side of the supernatural world and keep their otherworldly witchcraft a secret.