Populating the world on the eve of the twentieth century, menaced by a science-obsessed era and trying to ensure their survival, the Mushi cast their malevolent spell on humans and nature alike. Supernaturally connected to the basic essence of life and death, they are capable of inhabiting the body and soul’s deepest recesses and can only be detected by a Mushi master. The precociously white-haired Ginko has lost his youth and one eye studying the Mushi. Like a travelling doctor, he visits far away places to undo the Mushi’s deeds and to cure their victims. Meanwhile, in a secluded mansion, beautiful Tanyu records the history of the creatures. The guardian of the Mushi’s annals, she spends her days collecting accounts of these mystical beings as ink flows directly from her fingertip. But one day, the ink she uses to write her tales permeates her blood vessels and all the characters disappear from her precious scrolls. She has been infected by the Mushi and the time has come for Ginko to save her life and to restore the lost archives of a fading world.