Mike Cranshaw and Sue Claussen have a chance encounter when Sue checks into the roadside motel owned by Mike's parents in Arizona. What starts with a bottle of wine "compliments of management" soon evolves into a multi-layered, cross-country journey of two people looking for a sense of purpose. Mike, an aimless dreamer, bets it all on a trip to Sue's workplace in Maryland – only to find that she has no place for him in her carefully ordered life. Buttoned down and obsessed with making a difference in the world, Sue goes back to her yogurt mogul ex-boyfriend Jango, who promises her a chance to head his charity operations. But, having found something worth fighting for, Mike pits his hopes against Sue's practicality, and the two embark on a twisted, bumpy, freeing journey to discover that their place in the world just might be together.