Preeminent New York psychiatrist Dr. Nathan Conrad has a successful practice, a beautiful wife and a charming daughter. Making his way home for the Thanksgiving holiday, Conrad is summoned by a colleague to examine a young woman. Elisabeth Burrows presents a history of unexplained violence, failed treatments and misdiagnoses. In short, the kind of case Nathan used to live for before he went 'uptown.' Now he is Elisabeth's last chance before she is shipped off to a state institution. Nathan's skills and intuition begin to make headway into Elisabeth's case. Little does Nathan suspect that Elisabeth is tied to a danger that has closed in on him and his family. Nathan's daughter has been kidnapped by ruthless thieves, and to save her he must somehow unlock a 6-digit number locked away in Elisabeth's troubled mind. With his daughter's captors watching his every move, Nathan is constantly reminded: if he wants to see his daughter alive, he dare not say a single word.