Vince is depressed following his divorce, and so to cheer him up, six of his friends decide to take him on a trip to a remote village for a boy’s weekend. However when they arrive, they find the whole village overrun by psychotic, homicidal women affected by an airborne virus them that turns them into man-hating cannibals. After the guys' minibus driver goes crazy, they are left stranded in the countryside with only a group of man-eaters for company.