If hotel rooms could talk, we would marvel at the adventures lived within them. Weaving together seven stories from seven different decades, we journey into a time capsule of the past century from inside room 720, an extraordinary room in an anonymous city hotel. In 1921, the opening night of the hotel brings a new bride and her cruel and wealthy husband to the room, setting in motion forces that will impact its future inhabitants. The interlocking tales visit the room in its many incarnations over the years, but the heart of events lie in the decadent 1980s- a disposable plastic world where two strangers unite for a tryst of unexpected emotion, creating a crumbling oasis at the end of a dwindling era. It is only on New Year's Eve 1999, when a teenager arrives at the newly refurbished hotel with a self-destructive plan, that the long-buried secrets of Room 720 are unlocked.