Made first TV appearance as a dancer on "Soul Train"

Spotted by Spike Lee at the LA club Funky Reggae; approached her to appear in his film, "Do the Right Thing"

Made film debut in Lee's "Do the Right Thing" as Lee's Puerto Rican girlfriend

TV acting debut in HBO's "Criminal Justice"

Served as choreographer of the Fly Girls on FOX's sketch comedy series "In Living Color"

Had a recurring role on the TV series "WIOU" (CBS)

Had a major role in the hit comedy "White Men Can't Jump" opposite Wesley Snipes and Woody Harrelson

TV debut as executive producer (also hosted), "Rosie Perez Presents Society's Ride" (HBO)

Earned a Best Supporting Actress Oscar nomination for her portrayal of a airplane crash survivor in "Fearless"

Cast as Nicolas Cage's free-spending wife in "It Could Happen to You"

Directed by future husband Seth Zvi Rosenfeld in "A Brother's Kiss"

Created (also executive produced) the HBO original presentation "Subway Stories: Tales from the Underground"; also acted opposite Michael McGlone in the "Love on the A Train" segment

Had title role in "Perdita Durango"; the character of Perdita Durango appeared previously in David Lynch's movie "Wild at Heart" played by Isabella Rossellini

Co-produced "The 24 Hour Woman"; also starred as a TV talk show host

Lent her voice to the animated "Road to El Dorado"

Made official NYC stage acting debut in the play "References to Salvador Dali Make Me Hot"

Starred opposite John Leguizamo in "King of the Jungle"

Appeared in the HBO original movie "Lackawanna Blues" based on Ruben Santiago-Hudson autobiographical one man show

Debut as a documentary director, "You Soy Boricua, Pa'que tu lo Sepas!" (I'm Boricua, Just So You Know!), which traces the history of Puerto Rican culture from its beginnings

Cast in the Broadway revival of "The Ritz" directed by Joe Mantello

Played a crooked cop in the comedy "Pineapple Express"

Played John Leguizamo's wife in the crime drama "The Take"

Nominated for the 2008 Independent Spirit Award for Best Supporting Female (“The Take”)

Played a recurring role on NBC's "Lipstick Jungle"