At age four, moved with family to Chicago where her father managed the Second City for years

Lived with family on an artists' commune in Front Royal, Virginia

Hitchhiked across the country to San Francisco at age 15 with three other teens

Worked at Renaissance and Dickens fairs in San Francisco

Professional stage debut, "Metamorphosis", at the Story Theatre, Los Angeles

TV-movie debut in "Having Babies II" (ABC)

Miniseries debut, starred opposite Bette Davis in "The Dark Secret of Harvest Home" (NBC)

Screen acting debut with a bit part as a commune girl in "More American Graffiti"

TV debut as a regular, playing a daughter of Shirley Jones on the NBC hour-long comedy-drama series, "Shirley"

Had a popular song "Rosanna" written about her and recorded by the group Toto

Received enthusuastic notices as Tommy Lee Jones' girlfriend in NBC's "The Executioner's Song"; also released theatrically

First starring role in a feature film, John Sayles' "Baby, It's You"

Breakthrough performance as star of Susan Seidelman's "Desperately Seeking Susan"

Co-starred as young artist opposite shambling master painter Nick Nolte in Martin Scorsese's "Life Lessons" segment of "New York Stories"

Delivered a 'piercing' performance in Quentin Tarantino's "Pulp Fiction"

Played a kinky car accident victim in David Cronenberg's controversial "Crash"

Co-starred with Joe Pesci and Danny Glover in the comedy "Gone Fishin'"

Cast in Vincent Gallo's "Buffalo '66"

Had a small role opposite Sandra Bullock in "Hope Floats"

Starred opposite Melissa Gilbert in the TV movie "Switched at Birth"

Played Matthew Perry's hateful wife in "The Whole Nine Yards"

Starred opposite Nastassja Kinski in "Diary of a Sex Addict"

Feature directing debut with the critically acclaimed documentary "Searching For Debra Winger"

Appeared in episodes of "Will & Grace" (NBC) as Grace's neighbor Julie

Appeared as married socialite Sherry on several episodes of Showtime's "The L Word"

Helmed the musical documentary, "All We Are Saying" a compelling, personal look at what makes musicians tick

Played Nic in the drama, "What About Brian" by creator J.J. Abrams