Competed on and won "Ted Mack's Amateur Hour" with friends at age 14

Performed as teenager on "The Jackie Gleason Show"

Played one season of summer stock in Durango, CO in the mid-1960s

Made TV debut on "The Danny Thomas Hour"

Appeared in films "How Sweet It Is" and "The Savage Seven"

Played recurring role of Myrna Turner on the ABC sitcom, "The Odd Couple"

Starred as Laverne opposite Cindy Williams on the ABC sitcom "Laverne and Shirley"

TV directing debut, an episode of the sitcom "Working Stiffs"

Directed episodes of "Laverne and Shirley" toward the end of its run (date approximate)

Asked by Paramount to direct feature film, "The Joy of Sex" starring John Belushi; Belushi was then found dead and the film was made by Martha Coolidge in 1984

Feature directorial debut, "Jumpin' Jack Flash", a Whoopi Goldberg comedy vehicle

Directed Tom Hanks to his first Oscar nomination in "Big"

Feature executive producing debut, "Awakenings"; film earned a Best Picture Oscar nomination

Helmed "A League of Their Own", about the women's baseball league; film starred Geena Davis and Hanks and featured Rosie O'Donnell and Madonna in supporting roles

Suffered what may have been a heart attack

Began appearing with Rosie O'Donnell in a series of TV commercials for K-Mart

Signed three-year, first-look deal with Universal Pictures

Helmed "The Preacher's Wife", a remake of the 1942 film "The Bishop's Wife"; Marshall's version starred Denzel Washington, Whitney Houston and Courtney B Vance

Directed the comedy-drama "Riding in Cars With Boys", starring Drew Barrymore

Played Lieutenant Chevetone in the drama "Stateside" also starring Carrie Fisher and Rachael Leigh Cook

Received a Star on the Hollywood Walk of Fame (August)

Appeared in the Albert Brooks' comedy, "Looking for Comedy in the Muslim World"

Helmed a series of Dove shorts, headlined by Felicity Huffman; premiered at dovenight.com