Moved with family to Los Angeles at age four

Made film debut as extra in "The Harrad Experiment", starring her mother and featuring her future first husband, Don Johnson

Feature film acting debut, aged 17, in "Night Moves"

Played one of the beauty contestants in the superb satire "Smile"

TV miniseries debut, "Once an Eagle" (NBC)

Debut as series regular in the ABC series "Carter Country"

Starred with mother, Tippi Hedren, in "Roar" (produced by stepfather, Noel Marshall); filmed several years before release

Took a year's sabbatical to study acting with Stella Adler

Returned to features as the female lead of Brian De Palma's "Body Double"

Breakthrough leading role in Jonathan Demme's "Something Wild"

Guest starred in an episode of "Miami Vice", directed by Don Johnson, her once-and-future husband

Received a Best Actress Academy Award nomination for her performance as a Staten Island secretary with aspirations to succeed in business in the comedy "Working Girl", directed by Mike Nichols

Acted opposite Tom Hanks and Bruce Willis in the disastrous screen version of "Bonfire of the Vanities", helmed by De Palma

Starred opposite James Woods as lovers facing an unwanted pregnancy in the "Hills Like White Elephants" segment of the HBO special "Women & Men: Stories of Seduction"

Made first film with then-husband Don Johnson, "Paradise"

Was unfortunately miscast as an NYC cop who goes undercover in the Hassidic community in "A Stranger Among Us"

Undertook the role of Billie Dawn in an ill-fated remake of "Born Yesterday"

Delivered an effective turn as Bruce Willis' wife in "Nobody's Fool", also starring Paul Newman

Co-starred with Anjelica Huston in the CBS miniseries "Buffalo Girls"

Starred opposite future husband Antonio Banderas in the uneven comedy "Two Much"

Played the blowsy Charlotte Haze in Adrian Lyne's remake of "Lolita"; shown on Showtime in the USA

Selected by Revlon as spokesperson for line of cosmetics aimed at women over 35 years of age

Made pilot for the proposed CBS sitcom "Me and Henry"; series not picked up

Made cameo appearance as a movie star in Woody Allen's "Celebrity"

Offered a rich performance as a drug addicted criminal opposite James Woods in "Another Day in Paradise"

Portrayed Marion Davies in the HBO movie "RKO 281", about the making of "Citizen Kane"

Cast as an aspiring actress who murders her husband in "Crazy in Alabama", the feature directorial debut of Antonio Banderas

Starred as an attorney defending a rap musician accused of murder in "Shadow of Doubt" (aired on Cinemax)

Had title role of a mentally unstable woman who seeks an old sweetheart in "Loving Lulu"

Portrayed a veteran movie star kidnapped by a struggling independent filmmaker who forces her to star in his latest opus in "Cecil B. Demented", written and directed by John Waters

Cast as Eve in the film "Shade," which is set in the world of poker hustlers; also starring Sylvester Stallone and Gabriel Byrne

Signed on to play a lawyer who manipulates men in the CBS movie "Heartless" (lensed 2004)