During the 1990s, Meg Ryan was the queen of American romantic comedy — an updated Doris Day relentlessly touted as “America’s Sweetheart” for her wholesome heroines in a steady string of mating mix-ups. Ryan embodied the cute, bubbly but befuddled objects of desire in Nora Ephron-penned hits “When Harry Met Sally” (1989), “Sleepless in Seattle” (1993) and “You’ve Got Mail” (1998) – films which earned her the rare following of both male and female fans who either wanted to take her home to mom or be her best shopping buddy. Ryan regularly sought to explore new territory outside of her well-worn