Raised on NYC's Lower East Side

Performed for a year at the Edinburgh Festival

Broadway debut, "In the Summer House" co-starring Dianne Wiest

Film acting debut playing a British bouncer opposite Parker Posey in "Party Girl"

Cast as a drag queen in Nora Ephron's "Mixed Nuts"; again co-starring Parker Posey

TV-movie debut, "A Silent Betrayal" (CBS)

Acted in the CBS TV miniseries "Buffalo Girls"

Co-starred in the indie film "Denise Calls Up"

Played Anne Heche's ex-beau in "Walking and Talking"

Portrayed one of the kidnappers in Ron Howard's "Ransom"

Third film with Posey, "The Daytrippers"; played her garrulous writer-boyfriend

Originated role of accused killer Cotton Weary in Wes Craven's "Scream"

Portrayed an astrophysicist in Barry Levinson's "Sphere"

Reprised role as Cotton Weary in Craven's "Scream 2"

Offered amusing turn as the wigged-out deputy in "Phantoms," adapted by Dean Koontz from his novel

Appeared as Reese Witherspoon's boyfriend in Robert Benton's "Twilight"

Cast as the villain Iachimo and the god Jupiter in Shakespeare's "Cymbeline" performed in NYC's Central Park

Played a man whose wife engages in an affair in the 1960s-set "A Walk on the Moon"

Portrayed Orson Welles in the HBO movie "RKO 281," about the making of "Citizen Kane"; gained 25 pounds for the role and earned an Emmy nomination

Co-starred in "Spring Forward," Tom Gilroy's directorial debut; served as associate producer; made directorial debut filming a behind-the-scenes documentary about the making of the film

Reprised Cotton Weary for "Scream 3"

Returned to Broadway co-starring with Juliette Binoche in a revival of "Betrayal"

Had featured role in "Pay It Forward" starring Kevin Spacey and Helen Hunt

Co-starred opposite Jeanne Tripplehorn in "Dial 9 for Love"

Played Iago to Keith David's Othello in a New York Shakespeare Festival production Off-Broadway

Starred opposite Ben Affleck in "The Sum of All Fears" based on the Tom Clancy novels about CIA analyst Jack Ryan

Starred in the TV moive "Hitler: The Rise of Evil"

Starred as a U.S. soldiers who was kidnapped by the enemy, and brainwashed during the the Gulf War in "The Manchurian Candidate" directed by Jonathan Demme

Offered a Tony award winning performance in "Glengarry Glen Ross," Joe Mantello's high-octane revival of David Mamet's play

Starred in the HBO original movie "Lackawanna Blues" based on Ruben Santiago-Hudson autobiographical one man show

Made screenwriting and directing debut with "Everything Is Illuminated" about a young Jewish American man's journey to Ukraine to find the woman who saved his grandfather during World War II

Co-starred with Julia Stiles in the remake of "The Omen" taking over the role originally played by Gregory Peck

Co-starred in John Curran's adaptation of the Somerset Maugham novel, "The Painted Veil"

Joined the cast of "CSI" (CBS), in a recurring four-episode arc playing a seasoned CSI veteran

Cast in the Broadway production of Eric Bogosian's "Talk Radio"; earned a Tony nomination for Best Performance by a Leading Actor in a Play