TV debut as series regular on the short-lived ABC medical drama, "Birdland"

Made feature film debut in "Things I Never Told You"

Co-starred opposite Jim Carrey in the comedy, "The Cable Guy"; produced by her future husband Judd Apatow, whom she met while filming

Starred as Ursula opposite Brendan Fraser's "George of the Jungle"

Portrayed Jon Stewart's well-endowed fiance in the Adam Sandler comedy, "Big Daddy"

Appeared in the ensemble of "Perfume"

Starred opposite Jason Lee in "Stealing Harvard"

Cast in husband Judd Apatow's directorial debut, "The 40 Year-Old Virgin"

Played Katherine Heigl's sister in husband Judd Apatow's comedy, "Knocked Up"

Co-starred with Matthew Perry and Zac Efron in the high school-set comedy, "17 Again"

Co-starred with Adam Sandler in a film directed by her husband, "Funny People"