Grew up in New York City

Began acting at the age of three, at first in TV commercials

Signed to the Ford Modeling Agency

Made feature film debut in "Oedipus Wrecks", the Woody Allen-directed segment of the anthology feature, "New York Stories"

Moved with her family to Los Angeles

Landed role of Claudia in "Interview with a Vampire" at age 10

Made TV-movie debut in a small role in the NBC drama, "Darkness Before Dawn"

Episodic TV debut guesting on two episodes of the NBC drama series, "Sisters" in the role of Kitten Margolis

First large feature film role, as Claudia in "Interview With the Vampire"

Co-starred with Robin Williams in the box-office hit "Jumanji"

Appeared in the two-part CBS drama "Ruby Ridge: An American Tragedy" as Sara Weaver

Made TV series debut with recurring role on the hit NBC medical drama "ER"

Voiced the title character as a girl for the Fox animated feature "Anastasia"

Had amusing supporting role as a child actress drafted to play an Albanian refugee in "Wag the Dog"

Starred as an expectant teenager in the Lifetime movie "Fifteen and Pregnant"

Co-starred in "Small Soldiers" and "Strike/The Hairy Bird"

Played a beauty queen contestant in the mock documentary "Drop Dead Gorgeous"

Teamed with Michelle Williams as two high school students who stumble onto Watergate in the comedy "Dick"

Portrayed a cheerleader in "Bring It On"

Cast as a troubled rich girl who falls for a Hispanic classmate in "crazy/beautiful"

Portrayed Marion Davies in "The Cat's Meow"; premiered at Locarno Film Festival

Cast as Mary Jane Watson, the girlfriend of Peter Parker, in the Sam Raimi directed "Spider-Man"

Cast in the drama feature "Levity"

Starred as Betty Warren in "Mona Lisa Smile"

Co-starred with Jim Carrey and Mark Ruffalo in "Eternal Sunshine of the Spotless Mind"

Reprised role as Mary Jane for "Spider-Man 2"

Starred as tennis pro Lizzie Bradbury, opposite Paul Bettany in the romantic comedy "Wimbledon"

Cast as Claire, a quick-witted flight attendant in Cameron Crowe's "Elizabethtown" opposite Orlando Bloom

Starred in the title role for Sofia Coppola's "Marie-Antoinette" opposite Jason Schwartzman as Louis XVI

Once again teamed with Tobey Mcguire and director Sam Raimi to play Mary Jane for "Spider-Man 3"

Joined the ensemble of "How to Lose Friends & Alienate People"