First acting job was in a TV commercial for cottage cheese

Breakthrough stage role in Christopher Hampton's play "Faith, Hope and Charity"

American TV debut, "Traffik"; aired on PBS's "Masterpiece Theatre"

Starred as Catherine the Great on the TNT miniseries "Young Catherine"

Won acclaim for her portrayal of Nadya Alliluyeva, the wife of "Stalin" in the HBO biopic

Feature debut, Peter Greenaway's "The Baby of Macon"

First feature released in the US, "Nostradamus"

Breakthrough role in "Legends of the Fall" with Brad Pitt and Anthony Hopkins

Cast as Guenevere opposite Sean Connery's Arthur and Richard Gere's Lancelot in "First Knight"

Had title role in Sydney Pollack's ill-fated remake of "Sabrina"

Executive produced the documentary "Calling the Ghosts: A Story About Rape, War and Women"

Formed Indican Productions

Signed production deal with Fox Searchlight Pictures

Had lead in "Smilla's Sense of Snow"

Starred in Nikita Mikhalkov's epic "The Barber of Siberia"

Returned to the London stage in David Hare's "My Zinc Bed"

Acted opposite Vince Vaughn and Ed Harris in "The Prime Gig"; film released direct-to-video after screenings at film festivals

Had featured role in the Showtime movie "Varian's War"

Co-starred in the HBO film about the American women's suffrage movement, "Iron Jawed Angels"

Appeared in David Lynch's "Inland Empire"

Played Lindsay Lohan's mother in the thriller "I Know Who Killed Me"

Played Abigail Breslin's mother in the family film, "Kit Kittredge: An American Girl"

Re-teamed with Brad Pitt for David Fincher's "The Curious Case of Benjamin Button"