Film debut, "The Ages of Lulu", directed by Bigas Luna

Co-starred in Pedro Almodovar's "High Heels"

Reteamed with direcor Luna for "Jamon, Jamon"

Portrayed an oversexed man in Luna's "Golden Balls/Huevos de Oro"

Delivered change of pace turns in "The Detective and Death/El Detective y la Muerte" and "Numbered Days/Dias Contados"

Starred in "Mouth to Mouth/Boca a Boca"; released in USA in 1997

Reteamed with Almodovar for "Live Flesh"

English-language debut opposite Rosie Perez in "Perdita Durango"

Served as executive producer and star of "Los Lobos de Washington"

Starred as Cuban writer Reinaldo Arenas in "Before Night Falls"; received Best Actor Academy Award nomination

Had featured role in "The Dancer Upstairs", directed by John Malkovich; screened at Sundance

Co-starred in the award-winning feature "Monday's in the Sun"

Appeared opposite Tom Cruise in the thriller "Collateral"

Starred in "Mar Adentro/The Sea Inside" about the Life story of Spaniard Ramón Sampedro, who fought a 30-year campaign to win the right to end his life with dignity; received a Golden Globe nomination for Best Lead Actor (Drama)

Cast in Andy Garcia's independent film "The Lost City," centered around a club owner in Havana, Cuba, during the 50's

Played the sinister monk, Brother Lorenzo in Milos Forman's "Goya's Ghosts"

Offered an award winning performance as a murderous drug runner in the Coen brothers' "No Country for Old Men"

Played a lovesick romantic in Mike Newell's adaptation of "Love in the Time of Cholera"