Formed band "No Dought" with brother Eric his friend John Spence, as a co-vocalist with Spence

Began singing as lead vocalist, when John Spence committed suicide; opened for The Untouchables and Fishbone

Signed with Interscope Records, after Flea, the bassist of the Red Hot Chili Peppers recorded a demo for the band

Released their self-titled debut, but the album was far from a commercial success

Released second album The Beacon Street Collection

Released third and most successful album Tragic Kingdom, which topped the charts with its debut single, "Just A Girl"; Eric Stefani left the band to become an animator on "The Simpsons" (Fox)

Released Return of Saturn, which spawned hits "Ex-Girlfriend" and "Simple Kind of Life"

Along with the band, tapes voice overs for Fox's animated series "King of the Hill" playing themselves

Appears as the musical guest on "Saturday Night Live" with Eve for a performance of the rap singer's track "Let Me Blow Ya Mind"; the duo later recorded the single together

Released Rock Steady which topped the charts with the single "Hey Baby"

Founded and designed for the L.A.M.B. fashion label

Released The Singles 1992-2003, the band's first retrospective album featuring all their singles; also released "Rock Steady Live DVD" a live concert DVD filmed at two shows in Long Beach during the 2002 Rock Steady Tour

Made acting debut portraying Jean Harlow in Martin Scorsese's "The Aviator

Released first solo album Love, Angel, Music, Baby; earned four Grammy nominations in 2005, including Album of the Year

Released second solo album The Sweet Escape; earned a Grammy nomination in 2007 for her collaboration with Akon on "The Sweet Escape"