Moved to Washington, DC at age 10 when his father went to work for the State Department

Moved with family to Beirut, Lebanon

Evacuated to Athens, Greece when civil war broke out in Beirut

Attended high school in Athens, Greece

Moved to Los Angeles after graduating from college

Worked in the marketing department of Charles Band's Empire Pictures

Worked on the advertising campaigns for such films as "Space Sluts in the Slammer" and the "Ghoulies" series

Hosted various segments on Movietime (later E! Entertainment Television), a 24-hour entertainment cable network

Had a small role in the ABC TV-movie, "What Price Victory"

Hosted the short-lived game show, "College Mad House" (syndicated)

Created and hosted (also co-executive produced) "Best of the Worst" (FOX)

Hosted "The HBO International Report" on E! Entertainment Television

Became the first host of "Talk Soup" (E!), a daily compilation of talk show highlights; also produced and co-wrote

Hosted (also wrote and produced) the NBC late-night talk show, "Later with Greg Kinnear"

Feature debut as a talk show host in the Damon Wayans comedy "Blankman"

Cast as David Larrabee in Sydney Pollack's remake of Billy Wilder's 1954 classic "Sabrina"

First leading role in a feature film, "Dear God"

Cast as Jack Nicholson's homosexual neighbor Simon Bishop in James L. Brooks' "As Good As It Gets"; received Golden Globe, SAG and Oscar nominations for Best Supporting Actor

Played Garry Shandling's sleazy, conniving co-worker in Mike Nichols' "What Planet Are You From?"

Played a soap opera actor in "Nurse Betty" opposite Renee Zellweger

Co-starred as Tom, a man facing the end of his marriage in the HBO adaptation of Pulitzer-winning play "Dinner With Friends"

Co-starred in the Vietnam War drama "We Were Soldiers"

Cast as TV star Bob Crane in the feature film "Auto Focus"

Starred opposite Matt Damon as conjoined twins in the Farrelly brother's comedy "Stuck on You"

Co-starred with Rebecca Romijn-Stamos in the thriller "Godsend"

Cast opposite Billy Bob Thornton in the remake of 1976's "The Bad News Bears"

Co-starred with Pierce Brosnan and Hope Davis in "The Matador"

Co-starred with Toni Collette and Steve Carell in the comedy, "Little Miss Sunshine"

Cast as legendary football coach Dick Vermeil in "Invincible"

Played a fast food marketing executive in Richard Linklater's "Fast Food Nation"

Cast in Robert Benton's "Feast of Love" the ensemble drama, based on the novel by Charles Baxter

Cast opposite Tina Fey and Amy Poehler in the comedy, "Baby Mama"

Co-starred with Ricky Gervais in "Ghost Town"