Studied drama at Herbert Berghof Studios in NYC

Joined St. Nicholas Theater New Work Ensemble in Chicago

Co-starred with John Malkovich in the Chicago production of Sam Shephard's "The Curse of the Starving Class"

Joined Chicago's acclaimed Steppenwolf Ensemble

Feature film debut in Arthur Penn's "Four Friends"

First leading role, "Seize the Day"; aired on PBS's "Great Performances" and also released theatrically

Early TV work, lent her voice to the CBS animated children's special, "Santabear's Highflying Adventure"

Played female lead in "Dirty Rotten Scoundrels" as the target of a wager between con men Steve Martin and Michael Caine

Appeared in the CBS miniseries, "Lonesome Dove"

Joined an ensemble cast in the AIDS themed HBO drama, "And the Band Played On"

Joined the cast of NBC's medical drama "ER" as Dr. Abby Keaton

Cast as Nathan Lane's sister in the NBC sitcom, "Encore! Encore!"

Made London stage debut alongside Miranda Richardson in "Aunt Dan and Lemon"

Played a psychiatrist in Mike Figgis' experimental feature, "Time Code"

Co-starred with Alan Arkin and Lauren Holly in "Counting Sheep"

Cast as Lindsay Lohan's mother in the teen comedy "Confessions of a Teenage Drama Queen"

Co-starred in the black comedy "Eulogy"

Cast in the independent comedy "The Amateurs"

Re-teamed with Arkin and Holly for Neal Miller's character-driven film, "Raising Flagg"

Joined Abigail Breslin for the family film, "Kit Kittredge: An American Girl"