Performed with Mount Washington Repertory Theatre Company in New Hampshire in the late 1970s

After graduating from college, signed with the NYC-based Zoli modeling agency (date approxiomate)

Worked as waitress in NYC

TV series debut, played a recurring role on the hit NBC sitcom "Family Ties"

Screen acting debut in "Tootsie"

Debut as a series regular, played Wendy Killian on NBC's acclaimed but short-lived sitcom "Buffalo Bill"; also credited as writer for one episode

Made debut as a series star with "Sara", a short-lived NBC sitcom

First screen collaboration with future husband Jeff Boldblum whom she met during the shoot

First feature starring role, David Cronenberg's "The Fly," opposite Goldblum

Married Goldblum on November 1

Co-starred (with William Hurt) in Lawrence Kasdan's "The Accidental Tourist"; won Oscar for Best Supporting Actress

"Sara" rerun on NBC in the summer

Final screen collaboration with Goldblum before their 1990 divorce, Julien Temple's "Earth Girls Are Easy"

Founded production company, Genial Pictures, with partner Fanny Levy; made deal with Fox to develop own scripts and stories (date approximate)

Co-starred in controversial hit "Thelma & Louise"; garnered second Oscar nomination

Married transplanted Finnish action film director Renny Harlin

Formed Forge Productions with Renny Harlin

Starred in and co-produced feature film "Speechless"

Co-produced (with Renny Harlin) TV-movie "Mistrial" (HBO)

Split from Harlin and terminated her participation in Forge Productions

Hosted the Academy Awards telecast pre-show on ABC (March 21)

Played the mother in the feature adaptation of "Stuart Little"

Returned to the small screen as star of the fall ABC sitcom "The Geena Davis Show"

Reprised role as Mrs. Little in "Stuart Little 2"

Cast as the first female president of the United States in Rod Lurie's ABC drama "Commander in Chief"; earned a SAG (2006) nomination for Best Actress

Earned an Emmy nomination for Best Actress in a Drama Series for "Commander in Chief"