Early stage role, a romantic lead in "Lock Up Your Daughters"

Began stage career as Pable Gonzalez in the Bristol Old Vic's production of "A Streetcar Named Desire"

Performed at the National Theatre in "Bent" and "Abingdon Square"

Made film debut as Derek Bentley, a mentally-challenged teen accused of murder, in "Let Him Have It"

Made series debut, playing Detective Chief Inspector Bilborough, in "Cracker" (ITV)

Co-starred in Danny Boyle's "Shallow Grave"

Co-starred in the TV drama "Hearts and Minds" on BBC

Played title role in Michael Winterbottom's adaptation of "Jude"

Had leading role in the British TV drama "Our Friends in the North" (BBC)

Acted in the British TV movie "Hillsborough" (ITV)

Cast as an Hasidic Jew in "A Price Above Rubies"

Had featured role as the Duke of Norfolk in the Oscar-nominated biopic "Elizabeth"

Re-teamed with Winterbottom for "With or Without You"

Played the recipient of a transplant in "Heart"

Had supporting role in "eXistenZ"

Returned to the London stage in "Miss Julie"

Offered a villainous turn in "Gone in 60 Seconds"

Cast as the male lead in "The Invisible Circus"; screened at Sundance

Played Nicole Kidman's husband in the psychological drama "The Others"

Re-teamed with Danny Boyle for the British TV drama "Strumpet"

Again teamed with Boyle on the feature "28 Days Later"

Cast as the ninth incarnation of the Doctor in the revival of the legendary BBC series "Doctor Who"; left show after only one season

Joined the cast of NBC's "Heroes" as a character named Claude who has the power of invisibility

Cast as The Rider in a film adaptation of "The Dark Is Rising," retitled "The Seeker"

Cast as the villainous Destro in the live-action film "G.I. Joe: The Rise of Cobra"

Portrayed Fred Noonan, Earhart's navigator, in Mira Nair's biopic, "Amelia"