Raised in Montclair, New Jersey

Did voice-overs and appeared in TV commercials

Feature acting debut as Cher's youngest daughter in "Mermaids"

Breakthrough screen role as Wednesday in "The Addams Family"

Reprised role of Wednesday in "Addams Family Values"

Starred as a relatively 'normal' kid in "Casper"

Made cameo appearance in Anjelica Huston's "Bastard Out of Carolina" (aired on Showtime)

Played a troubled suburban teenager in "The Ice Storm"

Formed production company, Blaspheme Films

Earned rave reviews as a pregnant teenager who wreaks havoc, in the comedy-drama "The Opposite of Sex"

Played a kidnap victim who pretends to be her abductor's wife in Vincent Gallo's "Buffalo 66"

Had supporting role as the laundy-obsessed girlfriend of a photographer in John Waters' "Pecker"

Co-starred opposite Johnny Depp in "Sleepy Hollow"

Had pivotal role in the thriller "Bless the Child"

Reteamed with Depp for "The Man Who Cried"; premiered at the Venice Film Festival (released in US in 2001)

Co-produced and starred in the film adaptation of "Prozac Nation"

Cast in the HBO feature ensemble, "The Laramie Project"; adapted from Moises Kaufman's stage drama about the aftermath of the murder of Matthew Shepard

Featured (also produced) in "Pumpkin"; screened at the Sundance Film Festival

Had title role in the Sundance-screened "Miranda"

Feature directorial debut "Speed Queen" (lensed 2002); also starred

Had lead in Woody Allen's "Anything Else"

Played the lesbian lover of Charlize Theron's character in "Monster"

Starred in the Wes Craven werewolf movie "Cursed"

Guest-starred on "Joey" (NBC), playing Joey's (Matt LeBlanc) sister Mary Teresa

Earned an Emmy nomination for Best Guest Actress in a Drama Series for "Grey's Anatomy"

Cast in Irwin Winkler's "Home of the Brave," about the lives of four American soldiers in Iraq and their return back to the US

Portrayed a young woman addicted to sex who is kidnaped by Samuel L. Jackson in "Black Snake Moan"

Starred in "Penelope" as a cursed woman; produced by and co-starred Reese Witherspoon (lensed 2006)

Cast as Trixie, the female lead in the Wachowski brothers' live action film adaptation of the 1960s Japanese series "Speed Racer"