Raised in Rockland County, New York

Sang in a rock band while a high school student

Acted in off-off-Broadway productions after graduating from the American Academy of Dramatic Arts

Made feature film debut in "The Moderns"

TV acting debut, an episode of the CBS drama series "The Equalizer"

First major film role, "The Silence of the Lambs"

Won critical praise in "Walking the Dead" at NY's Circle Repertory Company

Rehearsed production of "Uncle Vanya" directed by Andre Gregory over a four and a half year period

Played Sonya in "Vanya on 42nd Street"

Appeared in "Trees Lounge"

Wrote, directed and starred in short feature "Sheep's Meadow"

Played Dawn Largato, the reigning champ of a fictional TV series in the satirical "Series 7"

Cast in the TV movie "Iron Jawed Angels"

Played one of Claire Fisher's art teachers in the HBO series, "Six Feet Under"

Cast in Woody Allen's "Melinda and Melinda"

Starred in the Curtis Hanson directed "In Her Shoes," adapted from Jennifer Weiner's best-selling novel

Joined the cast of Neil LaBute's off-Broadway play "Some Girl(s)," co-starring Eric McCormack

Had a recurring role as Dr. Erica Hahn in five episodes of "Grey's Anatomy's" (ABC) third season; became a regular cast member replacing Dr. Preston Burke as the hospital's head of cardiothoracics in the fourth season; character was written off just seven episodes into season five

Had a recurring role as Dr. Kate Switzer on "Crossing Jordan"

Cast opposite Kal Penn in director Mira Nair's "The Namesake," an adaptation of Jhumpa Lahiri best selling novel

Cast in a recurring role on the Showtime series, "Weeds," as the ex-wife of Peter Scottson