Moved to Ireland as an infant; lived at St Clerans, an estate in Galway

Moved to London at age ten (date approximate)

Auditioned for the role of Juliet in Franco Zeffirelli's film version of "Romeo and Juliet"; reportedly was considered for the role until father intervened allowing Olivia Hussey to be cast

Feature film acting debut an uncredited appearance in father's "Sinful Davey"

First starring film role, "A Walk With Love and Death", directed by her father (who also co-starred as her uncle, Robert the Elder); performance was panned by critics

Moved to NYC after mother's death and continued to understudy Marianne Faithful in the role of Ophelia for the Broadway production of "Hamlet", originally staged by Tony Richardson in England; appeared as a Court Lady when the vehicle was filmed

Began modeling for Vogue, among other magazines, when photographer (and old friend of Huston's mother) Richard Avedon asked her to do a 30-page fashion shoot in Ireland

Moved to Los Angeles

Returned to the screen in Elia Kazan's "The Last Tycoon" (based on F Scott Fitzgerald's unfinished novel), her first film with Jack Nicholson

Second film with Nicholson, Bob Rafelson's remake of "The Postman Always Rings Twice"; played a lion tamer

Involved in a serious car accident which refocused both her life and her acting ambitions

Acted in episodes of "Laverne and Shirley" (ABC), playing a model with an Eiffel Tower on her head in one

Had a small role in Rob Reiner's feature directing debut, "This Is Spinal Tap"

Career received a boost when cast as an Amazon with guns and swords on her hips in the space shoot-em-up "The Ice Pirates"

TV-movie debut, "The Cowboy and the Ballerina" (CBS)

Breakthrough screen role as the Mafia princess in "Prizzi's Honor", directed by father; third film with Nicholson; won Best Supporting Actress Oscar

Played title role in Los Angeles stage production of "Tamara"

Joined Michael Jackson and Dick Shawn in Francis Ford Coppola's 17-minute, 3-D musical fantasy short "Captain Eo", produced for showing at the Disney theme parks

Reunited with Coppola for "Gardens of Stone"; first leading role

Starred as a woman in a loveless marriage in father's last film, "The Dead", adapted by brother Tony from James Joyce's concluding short story in his youthful "Dubliners" collection

Acted in half-brother Danny's "Mr. North", co-adapted by father from Thornton Wilder's last novel

Received a Best Supporting Oscar nomination as a Nazi concentration camp survivor in Paul Mazursky's "Enemies, a Love Story"

First film with director Woody Allen, "Crimes and Misdemeanors", playing desperate (and eventually murdered) mistress of Martin Landau

Miniseries debut in a starring role, "Lonesome Dove" (CBS); earned first Emmy nomination; first time acting in a project adapted from the work of Larry McMurtry, author of the Pulitzer Prize-winning novel

Nominated for a Best Actress Academy Award nomination as the platinum-haired con artist in "The Grifters"

Acted the part of the Grand High Witch in Nicolas Roeg's "The Witches", based on the book by Roald Dahl

Portrayed the eerie-but-elegant Morticia Addams in "The Addams Family"

Appeared as herself in Robert Altman's "The Player"

Narrated the "Rip Van Winkle" segment of Showtime's "American Heroes & Legends"

Reprised Morticia for "Addams Family Values"

Reteamed with Allen for "Manhattan Murder Mystery"

Offered a strong performance as the mother of an autistic child in the ABC miniseries "Family Pictures"

Played Doctor Betsy Reisz in HBO's moving, acclaimed "And the Band Played On", which traced the course of the AIDS crisis

Reteamed with Nicholson to play an estranged couple in Sean Penn's "The Crossing Guard"

Portrayed Calamity Jane in the CBS minieries "Buffalo Girls", adapted from McMurtry's novel; earned second Emmy nomination

Made directorial debut with "Bastard Out of Carolina" and received an Emmy nomination for her efforts; film was originally shot for TNT but the network would not air it over the content; shown at the 1996 Cannes Film Festival; became Showtime's highest-rated program when it aired on that network later in the year

Played Vincent Gallo's Buffalo Bills-crazed mom in Gallo's "Buffalo 66"

Portrayed the evil stepmother in "Ever After", Andy Tennant's take on the Cinderella story

Acted in Danny Cannon's mediocre crime film "Phoenix" (HBO), portraying Ray Liotta's love interest

Directed, co-produced and starred in "Agnes Browne", playing a widowed mother of seven in 1960s Ireland

Appeared in James Ivory's "The Golden Bowl", based on the Henry James novel (and produced by Ismail Merchant with screenplay by Ruth Prawer Jhabvala); screened at Cannes

Portrayed the Lady in the Lake in the TNT feminist retelling of the Arthurian legend "The Mists of Avalon"

Played the matriarch in a family of failed geniuses in "The Royal Tenenbaums" directed by Wes Anderson

Starred opposite Clint Eastwood in "Blood Work" (lensed 2002)

Co-starred opposite Hilary Swank in the HBO movie "Iron Jawed Angels," about how American women got the vote in 1920; received an Emmy nomination for Outstanding Supporting Actress in a Miniseries or Movie (2004)

Co-starred with Bill Murray in Wes Anderson's "The Life Aquatic with Steve Zissou" as Zissou's (Murray) estranged wife

Directed Rosie O'Donnell and Andie MacDowell in the CBS movie "Riding the Bus With My Sister," based on the book of the same name

Guest-starred as an unorthodox psychiatrist in a four episode stint on the Showtime series "Huff"

Cast in Terry Zwigoff's adaptation of Daniel Clowes' comic story "Art School Confidential"

Co-starred with Liam Neeson and Pierce Brosnan in the western "Seraphim Falls"

Joined the cast of "Medium" for a six-episode story arc, playing a missing persons investigator; earned an Emmy nomination for Guest Actress in a Drama Series