Made professional acting debut in the National Tour of Neil Simon's “Biloxi Blues”

Had a short stint on the daytime drama “As the World Turns” (CBS)

Had a recurring role in the critically acclaimed drama “I'll Fly Away” (NBC) as a manipulative high school temptress

Broadway debut as Tessa Goode in “The Sisters Rosensweig”

Played Tea Leoni’s spoiled stepdaughter on the short-lived ABC sitcom, “The Naked Truth”

Replaced Calista Flockhart as Natasha in a revival of “The Three Sisters”

Feature film debut in the drama, “Roberta”

Received critical acclaim and her first Tony Award nomination for playing the love-starved Sonya in “Uncle Vanya”

Had a small role in the Oscar-nominated film, “You Can Count on Me”

Cast as Peggy in the Broadway revival of “The Women”

Landed a recurring role on the A&E crime drama, “100 Centre Street”; created by Sidney Lumet

Joined the cast of “The Wire” (HBO) in its second season, playing Port Authority Officer Beadie Russell

Played an impoverished single mother in the indie film, “Keane”

Received second Tony Award nomination for playing Stella Kowalski in “A Streetcar Named Desire”

Earned positive reviews as Chris Cooper’s star-struck wife in “Capote”

Reunited with Sidney Lumet for “Before the Devil Knows You’re Dead,” playing Ethan Hawke’s ex-wife

Received rave reviews for her portrayal of a drug-addicted mother whose child was abducted in Ben Affleck's directorial debut, "Gone Baby Gone"; earned Golden Globe, SAG and Oscar nominations for Best Supporting Actress

Had a recurring role on the NBC sitcom "The Office" as dorky HR rep Holly Flax

Played a prostitute wrongfully imprisoned by police in Clint Eastwood's "Changeling"