This attractive, openly gay young actor with large hazel eyes and a sensuous mouth is the second youngest of a showbiz dynasty. Alexis Arquette displayed a surprising acuity and maturity in his portrayal of the lovely, ironic young transvestite Georgette in "Last Exit to Brooklyn" (1989), his first major role in a feature. Growing up, Arquette lived in artists' colonies with his actor parents and siblings as well as in Los Angeles. As a young adolescent, he toured Europe as an actor and a dancer. Arquette was also impressive as Werner Hauser in the "American Playhouse" (PBS) production of "The Hollow Boy" (1991) and as Danny, Tim Roth's crack addicted brother, in "Jumpin' at the Boneyard" (1991). His other feature acting credits include "Of Mice and Men" (1992), "Grief" (1993) and "Pulp Fiction" (1994). Arquette delivered a sweet performance as a gay soap opera writer who reunites with college chums in the genial "I Think I Do" (1998) and continued to appear in a supporting roles in a steady slate of films, including "Bride of Chucky" (1998), "She's All That" (1999), "Spun" (2002) and "Wasabi Tuna" (2003), as well as high-camp appearances as the Roman Emperor Caligula on the syndicated series "Xena: Warrior Princess" in 2001.

Increasingly out and unabashed about his homosexuality, Arquette got big laughs as the androgynous Boy George-esque musician George opposite Adam Sandler in "The Wedding Singer" (1998) and soon went public as a flamoyant transvestite in his personal life, known for his outrageous outfits and inventive hairstyles. He soon found a steady slate of work playing transvestites, women or androgynous characters in such films as "The Movie Hero" (2003), "Killer Drag Queens On Dope" (2003) and "Lords of Dogtown" (2005), and on television in the Showtime series "Beggars and Choosers" as Larry/Lola in the 1999-2000 season, as well as on his sister-in-law Corteney Cox Arquette's series "Friends" and Howard Stern's "Son of the Beach."

Arquette is also an L.A. area underground cartoonist, his most famous strip being "Nico's Mobile Mole," about his friend, actress Nico Petrakis.